There were also no significant differences between groups on frailty status score, physical function, nutritional status, and the biochemical tests using MannWhitney test
But preclinical results do not guarantee equivalent outcomes in humans, and no responsible review of this compound should suggest otherwise
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Both of these GLP-1/glucagon co-agonists, one based on a glucagon-derived backbone [922] and the other based on an oxyntomodulin-derived sequence [923], had superior weight loss in obese rodents relative to matched analogs that were selective in activity towards GLP-1R
Contraception & Pregnancy Because delayed gastric emptying may affect absorption of oral contraceptives, alternative or backup contraception may be recommended